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LRP8 Promotes Colorectal Cancer Progression by Suppressing Ferroptosis through the SLC3A2/GPX4 Signalling Axis LRP8/SLC3A2/GPX4 promoting CRC

2025-07-25

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Colorectal cancer (CRC) persists as one of the most lethal malignancies worldwide, with therapeutic resistance representing a significant obstacle in clinical management. Ferroptosis, a form of programmed cell death triggered by iron accumulation and lipid peroxidation, has recently emerged as a promising target for cancer therapy. Although low-density lipoprote...

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Literature Corpus work: d7b3ccd5-c668-5270-8542-634a54630d63
DOI: 10.21203/rs.3.rs-6861954/v1

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LRP8 Promotes Colorectal Cancer Progression by Suppressing Ferroptosis through the SLC3A2/GPX4 Signalling Axis LRP8/SLC3A2/GPX4 promoting CRCDOI 10.21203/rs.3.rs-6861954/v1Read

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