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The argininosuccinate lyase gene exacerbates pyrethroid resistance in the major African vectors Anopheles funestus

2025-03-14

Abstract excerpt

<title>Abstract</title> <p>Escalating pyrethroid resistance in malaria vectors is jeopardizing malaria control. Deciphering its complex evolutionary mechanisms is paramount to mitigate its impact. Here, we demonstrate that over-expression and allelic variation of the argininosuccinate lyase (<italic>ASL)</italic> gene exacerbate pyrethroid resistance in <italic>Anopheles funestus</italic>. Multi-omics analyses re...

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Literature Corpus work
6aa66df8-c130-5726-ae8e-0fd1cb383b74
DOI
10.21203/rs.3.rs-6063665/v1
Open publication

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The argininosuccinate lyase gene exacerbates pyrethroid resistance in the major African vectors Anopheles funestusDOI 10.21203/rs.3.rs-6063665/v1
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