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Article

Overexpression and nonsynonymous mutations of UDP-glycosyltransferases are potentially associated with pyrethroid resistance in Anopheles funestus.

Genomics - 1 Mar 2024

Al-Yazeedi Talal, Muhammad Abdullahi, Irving Helen, Ahn Seung-Joon, Hearn Jack, Wondji Charles S

Abstract excerpt

UDP-glycosyltransferases (UGTs) enzymes are pivotal in insecticide resistance by transforming hydrophobic substrates into more hydrophilic forms for efficient cell elimination. This study provides the first comprehensive investigation of Anopheles funestus UGT genes, their evolution, and their association with pyrethroid resistance. We employed a genome-wide association study using pooled sequencing...

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Source

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Identifiers

PMID: 38266739
DOI: 10.1016/j.ygeno.2024.110798
PMCID: PMC10963899

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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