Article

An evolutionary perspective of DNA methylation patterns in skeletal tissues using a nonhuman primate model of osteoarthritis

2020-07-31

Abstract excerpt

<h4>Objective</h4> Epigenetic factors, such as DNA methylation, play an influential role in the development of the degenerative joint disease osteoarthritis (OA). These molecular mechanisms have been heavily studied in humans, and although OA affects several other animals in addition to humans, few efforts have taken an evolutionary perspective. This study explores the evolution of OA epigenetics by assessing the...

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Literature Corpus work: 6a36bc27-7245-515d-9d8d-37107fb260da
DOI: 10.1101/2020.07.31.231522

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