Article
Cardiac patch treatment alleviates ischemic cardiomyopathy correlated with reverting Piezo1/2 expression by unloading left ventricular myocardium
2022-05-08
Abstract excerpt
Pathologically elevated mechanical load promotes the adverse remodeling of left ventricle (LV) post myocardial infarction, which results in the progression from ischemic cardiomyopathy to heart failure. Cardiac patches could attenuate adverse LV remodeling by providing mechanical support to infarcted myocardium and border zone tissue. However, the mechanism of the translation from mechanical effects to favorable t...
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Identifiers and source
- Literature Corpus work
- 69ec950f-281f-5e98-a0f9-33c3f103ea9c
- DOI
- 10.1101/2022.05.08.490841