Article

In Silico Analyses Reveal the Relationship Between ROCK2 Mutations and Laterality Defects

2022-05-10

Abstract excerpt

Laterality defects is a class of congenital disorders resulting from abnormalities in left-right (L-R) axis patterning. Previous studies indicated that the duplication of Rho-associated coiled-coil containing protein kinase 2(ROCK2) had connection with laterality disorders in human and its knockdown led to significant L-R abnormalities in Xenopus and Zebrafish. In this study, we aimed to investigate the associatio...

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Literature Corpus work: 69c3f72b-b0e8-5486-b3e4-e2d05c7392c2
DOI: 10.21203/rs.3.rs-1622843/v1

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