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Article

Reciprocal Changes of H3K27Ac and H3K27me3 at the Promoter Regions of the Critical Genes for Endometrial Decidualization

1 Sept 2018

Abstract excerpt

AIM: Decidualization is essential for embryo implantation and placental development. We aimed to obtain transcriptome and epigenome profiles for primary endometrial stromal cells (ESCs) and in vitro decidualized cells. MATERIALS & METHODS: ESCs isolated from human endometrial tissues remained untreated (D0), or decidualized for 4 days (D4) and 8 days (D8) in the presence of 8-bromo-cAMP and progesterone. RESULTS:...

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PMID: 30212243
DOI: 10.2217/epi-2018-0006

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