Article

Genome-wide association study of borderline personality disorder identifies 11 loci and highlights shared risk with mental and somatic disorders

2024-11-13

Abstract excerpt

We conducted the largest genome-wide meta-analysis of borderline personality disorder (BPD) to date, with a discovery sample of 12,339 cases and 1,041,717 controls, and a replication study of 685 cases and 107,750 controls (all participants of European ancestry). We identified 11 independent associated genomic loci, and nine risk genes in the gene-based analysis. We observed a single-nucleotide polymorphism (SNP)...

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Literature Corpus work: 6933e9fa-8a96-5932-816d-f2a9665fecb0
DOI: 10.1101/2024.11.12.24316957

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