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Article

Evidence for a shared genetic contribution to loneliness and borderline personality disorder.

Translational psychiatry - 18 Dec 2023

Schulze Anna, Streit Fabian, Zillich Lea, Awasthi Swapnil, Hall Alisha S M, Jungkunz Martin, Kleindienst Nikolaus, Frank Josef, Schwarze Cornelia E, Dahmen Norbert, Schott Björn H, Nöthen Markus, Mobascher Arian, Rujescu Dan, Lieb Klaus, Roepke Stefan, Herpertz Sabine C, Schmahl Christian, Bohus Martin, Ripke Stephan, Rietschel Marcella, Lis Stefanie, Witt Stephanie

Abstract excerpt

Loneliness, influenced by genetic and environmental factors such as childhood maltreatment, is one aspect of interpersonal dysfunction in Borderline Personality Disorder (BPD). Numerous studies link loneliness and BPD and twin studies indicate a genetic contribution to this association. The aim of our study was to investigate whether genetic predisposition for loneliness and BPD risk overlap and whether genetic...

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Identifiers

PMID: 38105248
DOI: 10.1038/s41398-023-02705-x
PMCID: PMC10725864

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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