Article

Rv0810c: a genus-conserved, structurally ordered small protein of unknown function carrying DUF3073 in Mycobacterium tuberculosis

2026-08-19

Abstract excerpt

Small annotated open reading frames are the most neglected part of the functionally uncharacterised M. tuberculosis genome. We revisit Rv0810c, a 60-residue protein carrying the unknown-function domain DUF3073 (Pfam PF11273), flagged as an Actinobacteria-signature protein in 2006 but never studied since. Rv0810c is genuinely translated (detected in 11 of 16 M. tuberculosis proteomic datasets), with no significant...

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Literature Corpus work: 685d9602-fdda-5b14-aae0-0f05a5896d54
DOI: 10.64898/2026.08.18.745482

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