Back to search

Article

Clinical Utility of the Molecular Microscope Diagnostic System in a Real-World Transplant Cohort: Moving Towards a New Paradigm

2024-06-26

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objectives</h4> To evaluate the clinical implications of adjunctive molecular gene expression analysis (MMDx ) of biopsy specimens in heart transplant (HT ) recipients with suspected rejection. <h4>Introduction</h4> Histopathological evaluation remains the standard method for rejection diagnosis in HT. However, the wide interobserver variability combined with a relatively common inciden...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
6802a493-adc5-5d79-b60a-5f7e51f80ae5
DOI
10.1101/2024.06.24.24309444
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Clinical Utility of the Molecular Microscope Diagnostic System in a Real-World Transplant Cohort: Moving Towards a New ParadigmDOI 10.1101/2024.06.24.24309444
Relationship Between Donor Derived Cell-Free DNA and Tissue-Based Rejection-Related Transcripts In Heart TransplantationSemantic proximity
Molecular Diagnosis of Heart Allograft Rejection Using Intra-Graft Targeted Gene Expression Profiling: the heart HistoMX systemSemantic proximity
The Molecular Phenotype of Kidney Transplants: Insights From the MMDx Project.Semantic proximity
Comparing Plasma Donor–derived Cell-free DNA to Gene Expression in Endomyocardial Biopsies in the Trifecta-Heart StudySemantic proximity
Rejection Surveillance: Integrating Cell-Free DNA and Gene Expression Panels to Decrease Invasiveness in Routine Monitoring of Heart Transplant RecipientsSemantic proximity
The Trifecta Study: Comparing Plasma Levels of Donor-derived Cell-Free DNA with the Molecular Phenotype of Kidney Transplant Biopsies.Semantic proximity
Dynamic responses to rejection in the transplanted human heart revealed through spatial transcriptomicsSemantic proximity
Distinct Molecular Processes Mediate Donor-derived Cell-free DNA Release From Kidney Transplants in Different Disease StatesSemantic proximity
The Banff 2024 Kidney Meeting Report: Rejection as a spectrum of phenotypes and focus on differential diagnostic reasoning.Semantic proximity
Blood Gene Expression Profiling and Donor-derived Cell-free DNA to Noninvasively Diagnose Clinical and Subclinical Kidney Transplant Rejection: A Real-life Appraisal StudySemantic proximity
Is the Banff Human Organ Transplant panel ready for prime time?Semantic proximity
Promises and limits of biopsy-based transcriptomics in kidney transplantation: a clinical utility perspective.Semantic proximity
Select a neighboring publication to make it the new centre.