Article

Once yearly cell-based therapy for sustained and dose tunable delivery of monoclonal antibodies

2026-05-21

Abstract excerpt

Over 200 monoclonal antibodies (mAbs) are approved for clinical use, yet their therapeutic potential is constrained by dependence on repeated injections or infusions that drive non-adherence, limit access in low-resource settings, and generate peak–trough pharmacokinetics linked to adverse effects and reduced efficacy. Here, we developed an immunomodulatory encapsulated cell-based ‘biologics factory’ that overcome...

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Identifiers and source

Literature Corpus work: 67ccc39e-fcb9-5fd2-867c-52e3f4c43636
DOI: 10.64898/2026.05.19.726224

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