Article

DeepTrio: Variant Calling in Families Using Deep Learning

2021-04-06

Abstract excerpt

Every human inherits one copy of the genome from their mother and another from their father. Parental inheritance helps us understand the transmission of traits and genetic diseases, which often involve de novo variants and rare recessive alleles. Here we present DeepTrio, which learns to analyze child-mother-father trios from the joint sequence information, without explicit encoding of inheritance priors. DeepTri...

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Literature Corpus work: 67b95a68-64d7-5c93-93b3-24dd5115e6e3
DOI: 10.1101/2021.04.05.438434

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