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Structural and Antigenic Polymorphism of the 35- to 48-Kilodalton Merozoite Surface Antigen (MSA-2) of the Malaria Parasite <i>Plasmodium falciparum</i>

1991-02-01

Abstract excerpt

Merozoite surface antigen MSA-2 of the human parasite Plasmodium falciparum is being considered for the development of a malaria vaccine. The antigen is polymorphic, and specific monoclonal antibodies differentiate five serological variants of MSA-2 among 25 parasite isolates. The variants are grouped into two major serogroups, A and B. Genes encoding two different variants from serogroup A have been sequenced, an...

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Identifiers and source

Literature Corpus work
676326bf-7ba6-5f99-ba5d-5051118a17b4
DOI
10.1128/mcb.11.2.963-971.1991
Open publication

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Structural and Antigenic Polymorphism of the 35- to 48-Kilodalton Merozoite Surface Antigen (MSA-2) of the Malaria Parasite <i>Plasmodium falciparum</i>DOI 10.1128/mcb.11.2.963-971.1991
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