Back to search

Article

An immunoinformatic approach driven by experimental proteomics: in silico design of a subunit candidate vaccine targeting secretory proteins of Leishmania donovani amastigotes

2020-04-02

Abstract excerpt

<title>Abstract</title> <p>Background Visceral leishmaniasis (VL) caused by dimorphic Leishmania species is a parasitic disease with high socioeconomic burden in endemic areas worldwide. Sustaining control of VL in terms of proper and prevailing immunity development is a global necessity amid unavailability of a prophylactic vaccine. Screening of experimental proteome of the human disease propagating form of Leis...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
6654dc5e-cecd-55ee-ac5d-b82a09c19a4d
DOI
10.21203/rs.2.18586/v4
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
An immunoinformatic approach driven by experimental proteomics: in silico design of a subunit candidate vaccine targeting secretory proteins of Leishmania donovani amastigotesDOI 10.21203/rs.2.18586/v4
An immunoinformatic approach driven by experimental proteomics: in silico design of a subunit candidate vaccine targeting secretory proteins of Leishmania donovani amastigotesSemantic proximity
In-silico design of an immunoinformatics based multi-epitope vaccine against Leishmania donovaniSemantic proximity
Design of a multi-epitope subunit vaccine for immune-protection against Leishmania parasiteSemantic proximity
Design and evaluation of a novel multi-epitope antigen for evaluate the diagnostic immunity responses against Leishmania infantum infectionSemantic proximity
Prediction and analysis of promiscuous T cell-epitopes derived from the vaccine candidate antigens of Leishmania donovani binding to MHC class-II alleles using in silico approach.Semantic proximity
In silico designing of a novel polyvalent multi-subunit peptide vaccine leveraging cross- immunity against human visceral &amp; cutaneous leishmaniasis: An Immunoinformatics-based approachSemantic proximity
Mining the <b><i>Leishmania</i></b> genome for novel antigens and vaccine candidatesSemantic proximity
Investigation of Leish-111f Epitopes to Design a New Multi-epitope Vaccine Against Leishmania Major Using Immunoinformatics ApproachesSemantic proximity
In-silico design of a multi-epitope vaccine candidate against onchocerciasis and related filarial diseasesSemantic proximity
Immunoinformatics Features Linked to Leishmania Vaccine Development: Data Integration of Experimental and In Silico Studies.Semantic proximity
Multi-epitope vaccine design against leishmaniasis using IFN-γ inducing epitopes from immunodominant gp46 and gp63 proteinsSemantic proximity
Chimeric Vaccines Designed by Immunoinformatics-Activated Polyfunctional and Memory T Cells That Trigger Protection against Experimental Visceral LeishmaniasisSemantic proximity
Select a neighboring publication to make it the new centre.