Article
Immunoinformatics Features Linked to Leishmania Vaccine Development: Data Integration of Experimental and In Silico Studies.
International journal of molecular sciences - 10 Feb 2017
Brito Rory C F, Guimarães Frederico G, Velloso João P L, Corrêa-Oliveira Rodrigo, Ruiz Jeronimo C, Reis Alexandre B, Resende Daniela M
Abstract excerpt
Leishmaniasis is a wide-spectrum disease caused by parasites from Leishmania genus. There is no human vaccine available and it is considered by many studies as apotential effective tool for disease control. To discover novel antigens, computational programs have been used in reverse vaccinology strategies. In this work, we developed a validation antigen approach that integrates prediction of B and T cell...
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