Article

Mutations in the <i>Drosophila</i> splicing regulator <i>Prp31</i> as a model for Retinitis pigmentosa 11

2017-06-09

Abstract excerpt

Retinitis pigmentosa is a clinically heterogeneous disease affecting 1.6 million people worldwide. A growing number of identified disease-causing genes are associated with the spliceosome, but the molecular consequences that link defects in splicing factor genes to the aetiology of the disease remain to be elucidated. In this paper, we present a Drosophila model for Retinitis pigmentosa 11, a human disease caused...

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Literature Corpus work: 6635223a-b7f4-5219-9f22-f3cc1e8a8a38
DOI: 10.1101/147918

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