Article

The splicing regulator Prp31 prevents retinal degeneration in <i>Drosophila</i> by regulating Rhodopsin levels

2018-08-07

Abstract excerpt

Retinitis pigmentosa (RP) is a clinically heterogeneous disease affecting 1.6 million people worldwide. The second-largest group of genes causing autosomal dominant RP in human encodes regulators of the splicing machinery, but the molecular consequences that link defects in splicing factor genes to the aetiology of the disease remain to be elucidated. Mutations in PRPF31, one of the splicing factors, are linked to...

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Literature Corpus work: 9584c8fd-f4de-5e79-aa17-af09f4b343c6
DOI: 10.1101/386433

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