Article

The importance of erythroid expansion in determining the extent of apoptosis in erythroid precursors in patients with β-thalassemia major

2000-11-15

Abstract excerpt

Abstract Beta-thalassemia major is characterized by ineffective erythropoiesis leading to severe anemia and extensive erythroid expansion. The ineffective erythropoiesis is in part due to accelerated apoptosis of the thalassemic erythroid precursors; however, the extent of apoptosis is surprisingly variable. To understand this variability as well as the fact that some patients undergoing allogeneic marrow transpla...

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Literature Corpus work: 661dd933-73b0-5cb6-a34f-db18a7d11b65
DOI: 10.1182/blood.v96.10.3624

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