Article
Annexin A2 positively contributes to the malignant phenotype and secretion of IL-6 in DU145 prostate cancer cells.
International journal of cancer - 1 Jan 2009
Inokuchi Junichi, Narula Navneet, Yee David S, Skarecky Douglas W, Lau Alice, Ornstein David K, Tyson Darren R
Abstract excerpt
Several groups, including ours, have reported that annexin A2 (ANXA2) expression is reduced in most prostate cancer (CaP). More recently, however, we reported that ANXA2 is expressed in some high-grade tumors, but the biologic consequence of this is currently unknown. To elucidate the function of ANXA2 in CaP, we reduced its expression in DU145 cells using shRNA and tested the impact on characteristics of...
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