Back to search

Article

Antivirals and Biologics for Broader Coverage Against Human Coronaviruses

2023-12-12

Abstract excerpt

Coronaviruses (CoVs) are enveloped positive-sense single-stranded RNA viruses with a genome 27-31kbases in length. Critical genes include the spike (S), envelope (E), membrane (M), nucleocapsid (N) and 9 accessory open reading frames encoding for non-structural proteins (NSPs) that have multiple roles in the replication cycle and immune evasion (1). There are 7 known human CoVs that most likely appeared after zoon...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
7036662d-923f-57ba-80a2-47fc84d2d8a4
DOI
10.20944/preprints202312.0712.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Antivirals and Biologics for Broader Coverage Against Human CoronavirusesDOI 10.20944/preprints202312.0712.v1
The recent outbreaks of human coronaviruses: A medicinal chemistry perspectiveSemantic proximity
Existing Antiviral Options Against SARS-CoV-2 Replication in COVID-19 PatientsSemantic proximity
Recent advances in small-molecular therapeutics for COVID-19Semantic proximity
Current status of antivirals and druggable targets of SARS CoV-2 and other human pathogenic coronavirusesSemantic proximity
Coronavirus in human diseases: Mechanisms and advances in clinical treatmentSemantic proximity
Potential Broad-Spectrum Antiviral Agents: A Key Arsenal Against Newly Emerging and Reemerging Respiratory RNA VirusesSemantic proximity
TMPRSS2 and RNA-Dependent RNA Polymerase Are Effective Targets of Therapeutic Intervention for Treatment of COVID-19 Caused by SARS-CoV-2 Variants (B.1.1.7 and B.1.351)Semantic proximity
Druggable targets and therapeutic development for COVID-19Semantic proximity
A comprehensive review on efficient approaches for combating coronaviruses.Semantic proximity
There Was No New Needle in the COVID Therapeutic Haystack A COVID-19 Therapeutics AnalysisSemantic proximity
Approaches to the Potential Therapy of COVID-19: A General Overview from the Medicinal Chemistry PerspectiveSemantic proximity
Navigating the COVID-19 Therapeutic Landscape: Unveiling Novel Perspectives on FDA-Approved Medications, Vaccination Targets, and Emerging Novel StrategiesSemantic proximity
Select a neighboring publication to make it the new centre.