Article

The Mortality Fuse: Immune Conditioning as a Driver of Human Longevity

2026-06-19

Abstract excerpt

<title>Abstract</title> <p>Conditions with immunological features are viewed as liabilities of aging. We hypothesized that, in combination, these conditions define a regulated immune phenotype associated with reduced mortality and slower cognitive decline. We harmonized seven independent resources spanning clinical cohorts, aging studies, and mortality registries. A Protective Diagnosis Score (PDS) was defined as...

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Literature Corpus work: 65cebe46-1663-559c-aa07-9602df32cff9
DOI: 10.21203/rs.3.rs-9741847/v1

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