Article

The age paradox in post-infectious sequelae: physiological reserve outweighs chronological age in Long COVID susceptibility

2026-02-26

Abstract excerpt

<h4>Background</h4> Older age is widely considered a risk factor for post-acute sequelae of SARS-CoV-2 infection (PASC), typically attributed to immunosenescence and inflammaging. However, whether this association reflects intrinsic biological ageing or accumulated comorbidity burden remains unclear, with implications for clinical risk stratification. <h4>Methods</h4> We conducted a retrospective cohort study us...

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Literature Corpus work: 27021955-1bdd-5a72-959f-19ce189c7bf0
DOI: 10.64898/2026.02.24.26346989

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