Back to search

Article

CD147 ( <i>BSG</i> ) but not <i>ACE2</i> expression is detectable in vascular endothelial cells within single cell RNA sequencing datasets derived from multiple tissues in healthy individuals

2020-05-29

Abstract excerpt

<h4>ABSTRACT</h4> Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and is associated with a wide range of systemic manifestations. Several observations support a role for vascular endothelial dysfunction in the pathogenesis including an increased incidence of thrombotic events and coagulopathy and the presence of vascular risk factors as an independent...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
65c67f5e-215d-5096-829a-d3d519a9b101
DOI
10.1101/2020.05.29.123513
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
CD147 ( <i>BSG</i> ) but not <i>ACE2</i> expression is detectable in vascular endothelial cells within single cell RNA sequencing datasets derived from multiple tissues in healthy individualsDOI 10.1101/2020.05.29.123513
Distribution of ACE2, CD147, cyclophilins, CD26 and other SARS-CoV-2 associated molecules in human tissues and immune cells in health and diseaseSemantic proximity
Gene expression and <i>in situ</i> protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissueSemantic proximity
Systemic analysis of putative SARS-CoV-2 entry and processing genes in cardiovascular tissues identifies a positive correlation of BSG with age in endothelial cellsSemantic proximity
<i>ACE2</i> and <i>TMPRSS2</i> expression by clinical, HLA, immune, and microbial correlates across 34 human cancers and matched normal tissues: implications for SARS-COV-2 COVID-19Semantic proximity
Lack of evidence of ACE2 expression and replicative infection by SARS-CoV-2 in human endothelial cellsSemantic proximity
Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissueSemantic proximity
BSG/CD147 and ACE2 Receptors Facilitate Direct SARS-CoV-2 Infection of Human iPS Cell-Derived Kidney PodocytesSemantic proximity
Resistance of endothelial cells to SARS-CoV-2 infection <i>in vitro</i>Semantic proximity
BSG/CD147 and ACE2 receptors facilitate SARS-CoV-2 infection of human iPS cell-derived kidney podocytesSemantic proximity
SARS-CoV-2 host receptors ACE2 and CD147 (BSG) are present on human oocytes and blastocystsSemantic proximity
miR-98 Regulates TMPRSS2 Expression in Human Endothelial Cells: Key Implications for COVID-19Semantic proximity
P-Selectin promotes SARS-CoV-2 interactions with platelets and the endotheliumSemantic proximity
Select a neighboring publication to make it the new centre.