Article

Cell composition inference and identification of layer-specific transcriptional profiles with POLARIS

2022-12-12

Abstract excerpt

Spatial transcriptomics (ST) technology, providing spatially resolved transcriptional profiles, facilitates advanced understanding of key biological processes related to health and disease. Sequencing-based ST technologies provide whole-transcriptome profiles, but are limited by the non-single cell level resolution. Lack of knowledge in the number of cells or cell type composition at each spot can lead to invalid...

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Literature Corpus work: 659a2b4a-c727-5c9e-9824-7ac633383bed
DOI: 10.1101/2022.12.08.519631

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