Article

High endothelial venules in intracranial germinomas: implications for lymphocytes infiltration

2022-04-18

Abstract excerpt

<title>Abstract</title> <p>Background Reactive lymphocytes are substantial components of germinoma, which are believed to be related to the favorable prognosis of this intracranial tumor and better response to immunotherapy. However, the mechanisms managing the recruitment of lymphocytes are poorly understood. High endothelial venules (HEVs) are specialized blood vessels that play key roles in lymphocyte traffic...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 659079c7-af9b-54f5-9ace-cb096471cada
DOI: 10.21203/rs.3.rs-1473457/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

High endothelial venules in intracranial germinomas: implications for lymphocytes infiltrationDOI 10.21203/rs.3.rs-1473457/v1Read

Anticancer immunotherapies transition postcapillary venules into high-endothelial venules that generate TCF1+ T lymphocyte niches through a feed-forward loopSemantic proximity Read

Lymphatic malformations revisited: Genetics, clinics and future directionsSemantic proximity Read

Research Advances of Germinal Matrix Hemorrhage: An Update ReviewSemantic proximity Read

Meningeal Lymphatics: An Immune Gateway for the Central Nervous System.Semantic proximity Read

How we approach the diagnosis and management of complex lymphatic anomaliesSemantic proximity Read

Number of glioma polyploid giant cancer cells (PGCCs) associated with vasculogenic mimicry formation and tumor grade in human gliomaSemantic proximity Read

Preoperative MRI diagnosis of lhermitte-duclos disease: Case report with associated enlarged vessel and syrinxSemantic proximity Read

A clinicopathological reappraisal of orbital vascular malformations and distinctive GJA4 mutation in cavernous venous malformations.Semantic proximity Read

Dynamic stroma reorganization drives blood vessel dysmorphia during glioma growth.Semantic proximity Read

Cerebrovascular Anomalies: Perspectives From Immunology and Cerebrospinal Fluid Flow.Semantic proximity Read

Immunological and Genomic Analysis Reveals Clinically Relevant Distinctions between Angiosarcoma SubgroupsSemantic proximity Read

Dual PD-L1/TIGIT blockade induces PNAd⁺ HEV-like vessels and CD62L⁺ lymphocyte recruitment, driving rhabdoid tumor rejectionSemantic proximity Read