Article

Honokiol and alfa-Mangostin inhibit Mayaro virus replication by stimulating the type I interferon pathway

2022-08-21

Abstract excerpt

<h4>ABSTRACT</h4> Mayaro virus (MAYV) is an emerging arbovirus with increasing circulation across the Americas. In the present study, we evaluated the potential antiviral activity of the following natural compounds against MAYV and other arboviruses: Sanguinarine, (R)-Shikonin, Fisetin, Honokiol, Tanshinone IIA and α-Mangostin. Sanguinarine and Shikonin showed significant cytotoxicity, whereas Fisetin, Honokiol,...

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Literature Corpus work: 65890bf8-e547-5ebd-853d-b4e8aab602eb
DOI: 10.1101/2022.08.20.504652

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