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Inhibitory Effect of Alpha-Mangostin to Dengue Virus Replication and Cytokines Expression in Human Peripheral Blood Mononuclear Cells

19 Sept 2019

Abstract excerpt

Massive pro-inflammatory cytokines production has been correlated with the pathogenesis of severe dengue disease. The active compound of mangosteen fruit pericarps, α-mangostin, has been commonly used as traditional medicine and dietary supplement. We examined the effect of α-mangostin against dengue virus (DENV) infection in human peripheral blood mononuclear cells (PBMC) by the measurement of virus titer and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31538308
DOI: 10.1007/s13659-019-00218-z

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