Article

Chrysin Alleviates DNA Damage to Improve Disturbed Immuno-Homeostasis and Pro-Angiogenic Environment in Laser-Induced Choroidal Neovascularization

2021-08-31

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Choroidal neovascularization (CNV) is a devastating pathology of numerous ocular diseases, such as wet age-related macular degeneration (wAMD), which causes irreversible vision loss. Although anti-VEGF therapy has been widely used, poor response or no response exits in some patients, suggesting that some other important angiogenic components play roles. Therefor...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 65366a53-6dd5-578d-95ff-be5ce5a2d1df
DOI: 10.21203/rs.3.rs-827729/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Chrysin Alleviates DNA Damage to Improve Disturbed Immuno-Homeostasis and Pro-Angiogenic Environment in Laser-Induced Choroidal NeovascularizationDOI 10.21203/rs.3.rs-827729/v1Read

Chrysin alleviates DNA damage to improve disturbed immune homeostasis and pro-angiogenic environment in laser-induced choroidal neovascularizationSemantic proximity Read

Photobiomodulation reduces the cytokine storm syndrome associated with Covid-19 in the zebrafish modelSemantic proximity Read

Comprehensive transcriptomic analysis reveals canonical and novel pathways modulated by nanoceria in mammalian retinal degenerationSemantic proximity Read

CircMETTL3 inhibits H2O2-induced senescence, oxidative stress, and DNA damage in ARPE-19 cells via miR-100/BMPR2 axisSemantic proximity Read

Oxidative Stress Susceptibility, Complement Dysregulation, and Metabolic Reprogramming in CFH Y402H Patient-Derived Choriocapillaris Endothelial CellsSemantic proximity Read

Expression of Pro-Angiogenic Markers Is Enhanced by Blue Light in Human RPE CellsSemantic proximity Read

Dasatinib Plus Quercetin Alleviates Choroid Neovascularization by Reducing the Cellular Senescence Burden in the RPE–ChoroidSemantic proximity Read

Photosensitization of A2E triggers telomere dysfunction and accelerates retinal pigment epithelium senescenceSemantic proximity Read

Comparative Analysis of Molecular Landscape in Mouse Models and Patients Reveals Conserved Inflammation Pathways in Age-Related Macular DegenerationSemantic proximity Read

Evaluation of sex differences in laser-induced choroidal neovascularization severity, phenotype and disease progressionSemantic proximity Read

Involvement of microRNAs as a Response to Phototherapy and Photodynamic Therapy: A Literature ReviewSemantic proximity Read

Role of Activating Transcription Factor 4 in Murine Choroidal Neovascularization ModelSemantic proximity Read