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Dimensional reduction of phenotypes from 53,000 mouse models reveals a diverse landscape of gene function

2021-06-10

Abstract excerpt

Animal models have long been used to study gene function and the impact of genetic mutations on phenotype. Through the research efforts of thousands of research groups, systematic curation of published literature, and high-throughput phenotyping screens, the collective body of knowledge for the mouse now covers the majority of protein-coding genes. We here collected data for over 53,000 mouse models with mutations...

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Literature Corpus work
652be97a-8d01-51e4-b66b-7e896d076da8
DOI
10.1101/2021.06.10.447851
Open publication

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Dimensional reduction of phenotypes from 53,000 mouse models reveals a diverse landscape of gene functionDOI 10.1101/2021.06.10.447851
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