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Acute testicular hyperthermia leads to a rapid loss of global piRNA levels and a consequent increase in transcript abundance, including LINE1 activity within heat-sensitive male germ cells

2025-03-31

Abstract excerpt

<h4>Objective</h4> To understand the immediate impact that testicular heat stress has on isolated populations of precursor male germ cells including Spermatocytes and Spermatids. <h4>Design</h4> Mice were given testicular heat stress and pre-cursor male germ cells were immediately isolated. RNA sequencing was performed and validated using qPCR. <h4>Subjects</h4> This work was carried out in adult male CD1 mice....

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Literature Corpus work
649ce5b8-93a9-5240-8ae2-0cc19b3f1189
DOI
10.1101/2025.03.30.646213
Open publication

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Acute testicular hyperthermia leads to a rapid loss of global piRNA levels and a consequent increase in transcript abundance, including LINE1 activity within heat-sensitive male germ cellsDOI 10.1101/2025.03.30.646213
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