Article
A single, mild, transient scrotal heat stress causes DNA damage, subfertility and impairs formation of blastocysts in mice
11 Apr 2008
Abstract excerpt
Infertility represents a major clinical problem and 50% of cases are attributable to the male partner. Testicular function is temperature dependent, and in both man and mouse the position of the testes in the scrotum ensures that they are kept at between 2 and 8 degrees C below core body temperature. We used a mouse model to investigate the impact of a single, transient, mild, scrotal heat stress (38, 40 or 42...
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