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Heat stress induced piRNA alterations in pachytene spermatocytes and round spermatids

24 Jul 2024

Abstract excerpt

BACKGROUND: Spermatogenesis is a temperature-sensitive process, and elevation in temperature hampers this process quickly and significantly. We studied the molecular effects of testicular heating on piRNAs and gene expression in rat testicular germ cells. METHODS: We generated a cryptorchid rat model by displacing the testis from the scrotal sac (34 °C) to the abdominal area (37 °C) and sacrificed animals after 1...

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PMID: 39049033
DOI: 10.1186/s12958-024-01249-z

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