Article

Generation of a Sleeping Beauty transposon-based cellular system for rapid and sensitive identification of SARS-CoV-2 host dependency and restriction factors

2021-04-27

Abstract excerpt

<h4>Summary</h4> The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the causative agent of the acute respiratory disease COVID-19, which has become a global concern due to its rapid spread. The common methods to monitor and quantitate SARS-CoV-2 infectivity in cell culture are so far time-consuming and labor-intensive. Using the Sleeping Beauty transposase system, we generated a robust and versat...

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Literature Corpus work: 644d4f1c-5bac-5261-832a-f70712346633
DOI: 10.1101/2021.04.27.441606

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