ARHGAP44 gene: a cytoskeleton mobility related modulator with potential implication in pan-cancer prognosis risk prediction and immune regulation

Abstract excerpt

<title>Abstract</title> <p>Background Rho GTPases has been a well known family of small G proteins that regulate cellular cytoskeleton dynamics and involve in multiple critical steps of cancer progression. However, ARHGAP44 gene which is a member of GAP proteins that regulates the Rho GTPases cycling between their active GTP-bound and inactive GDP-bound state, its role in cancer development is still lack of unde...

Topics

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• Alternative Splicing
• cdc42 GTP-Binding Protein
• Cellular Mechanics and Interactions
• Erythrocyte Function and Pathophysiology
• Genes
• GTPase-Activating Proteins
• Introns
• Protein Kinase Regulation and GTPase Signaling

Identifiers and source

Literature Corpus work

64187732-2fd4-5b2c-85c5-2d4659954926

DOI

10.21203/rs.3.rs-4288781/v1