Article

Anti-TRIM72 Autoantibodies in Idiopathic Inflammatory Myopathies

2025-07-24

Abstract excerpt

<h4>Background and Purpose</h4> Tripartite motif-containing protein 72 (TRIM72) mediates tissue-repair following injury in several organs, including muscle and lung. Autoantibodies directed against TRIM72 (anti-TRIM72) have been identified in patients with idiopathic inflammatory myopathies (IIM) and disrupt TRIM72 function in vitro. We hypothesized that IIM patients positive for anti-TRIM72 antibodies would have...

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Literature Corpus work: 6417a11e-a428-583a-926b-7209ba77f141
DOI: 10.1101/2025.07.23.25332079

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