Back to search

Article

Genome analysis of clinical pneumococcal isolates to decipher sequence types, antibiotic resistance mechanisms and virulence gene profiles

2020-07-21

Abstract excerpt

<h4>Introduction</h4> Streptococcus pneumoniae is a common cause of meningitis and pneumonia. Various studies have explored the relationship between genome and phenotypic characteristics like antibiotic resistance. <h4>Methods</h4> Four pneumococcal isolates from clinical specimens were included. DNA was extracted and genomes were sequenced in 2×101bp layout. Standard genome analysis tools and pipelines were em...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
6413e069-5387-529a-af81-5463f34096f3
DOI
10.1101/2020.07.21.211649
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Genome analysis of clinical pneumococcal isolates to decipher sequence types, antibiotic resistance mechanisms and virulence gene profilesDOI 10.1101/2020.07.21.211649
Whole-genome sequencing, strain composition, and predicted antimicrobial resistance of Streptococcus pneumoniae causing invasive disease in England in 2017–20: a prospective national surveillance studySemantic proximity
Annotated Draft Genomic Sequence from a Streptococcus pneumoniae Type 19F Clinical IsolateSemantic proximity
Molecular epidemiology of Streptococcus Pneumoniae isolated from children with community-acquired pneumonia under 5 years in Chengdu, ChinaSemantic proximity
International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impactSemantic proximity
Genomic epidemiology and antimicrobial susceptibility of clinical Mycoplasma pneumoniae isolates in Shanghai, 2023-2024.Semantic proximity
Molecular Characterization Based on Whole-Genome Sequencing of Streptococcus pneumoniae in Children Living in Southwest China During 2017-2019Semantic proximity
Identifying <i>Streptococcus pneumoniae</i> genes associated with invasive disease using pangenome-based whole genome sequence typingSemantic proximity
Evidence of virulence and antimicrobial resistance in <i>Streptococcus pneumoniae</i> serotype 16F lineagesSemantic proximity
Development of the Pneumococcal Genome Library, a core genome multilocus sequence typing scheme, and a taxonomic life identification number barcoding system to investigate and define pneumococcal population structureSemantic proximity
Using whole genome sequencing to identify resistance determinants and predict antimicrobial resistance phenotypes for year 2015 invasive pneumococcal disease isolates recovered in the United States.Semantic proximity
Genomic classification and antimicrobial resistance profiling of Streptococcus pneumoniae and Haemophilus influenzae isolates associated with paediatric otitis media and upper respiratory infectionSemantic proximity
A Portable and Scalable Genomic Analysis Pipeline for <i>Streptococcus pneumoniae</i> Surveillance: GPS PipelineSemantic proximity
Select a neighboring publication to make it the new centre.