Article

Epidermal TRPV4 ion channels regulate UVB induced sunburn by triggering inflammmasome activation and ERK signaling

2021-01-10

Abstract excerpt

<h4>ABSTRACT</h4> Skin inflammation is an evolutionary-honed protective mechanism that serves to clear noxious cues and irritants and initiate regeneration. Calcium-permeable transient-receptor-potential (TRP) ion channels have critical functions in sensory transduction which is sensitized in skin inflammation. Skin sensory transduction relies on skin-innervating sensory neurons in the dorsal root ganglion (DRG),...

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Literature Corpus work: 63caad39-90f2-5ad9-b393-ef84426e7f99
DOI: 10.1101/2021.01.09.426056

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