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Single variant bottleneck in the early dynamics of <i>H. influenzae</i> bacteremia in neonatal rats questions the theory of independent action

2016-09-16

Abstract excerpt

There is an abundance of information about the genetic basis, physiological and molecular mechanisms of bacterial pathogenesis. In contrast, relatively little is known about population dynamic processes, by which bacteria colonize hosts and invade tissues and cells and thereby cause disease. In an article published in 1978, Moxon and Murphy presented evidence that, when inoculated intranasally with a mixture strep...

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Literature Corpus work
63ad9374-de32-5901-936e-fdeac960f19b
DOI
10.1101/075531
Open publication

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Single variant bottleneck in the early dynamics of <i>H. influenzae</i> bacteremia in neonatal rats questions the theory of independent actionDOI 10.1101/075531
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