Article
The human pathogen, Schistosoma mansoni, lacks the cognate sequence for human telomerase reverse transcriptase (hTERT) and relies on the snail host, Biomphalaria glabrata homologous enzyme for its intra-molluscan development.
2023-06-26
Abstract excerpt
The human telomerase reverse transcriptase (hTERT) is the catalytic sub-unit of the ribonuclear protein, telomerase. Together with telomerase RNA, the enzyme complex participates in the maintenance of telomeres at the proximal ends of chromosomes, adding species-specific repeats to the 3’end of the telomere. The regulation of hTERT is tightly linked to the cell cycle and cell differentiation states governing eithe...
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Identifiers and source
- Literature Corpus work
- 63a00e4c-e30e-560a-9a1c-c59a3c275fcf
- DOI
- 10.21203/rs.3.rs-3069723/v1
