Back to search

Article

Meta-analysis of functional genomics studies reveals conserved cellular pathways required by viruses of pandemic concern

2026-01-14

Abstract excerpt

The COVID-19 pandemic illustrated the need to develop medical countermeasures against emerging infectious diseases. As viruses rely on cellular machinery for replication, host-directed antivirals (HDAs) may complement conventional antiviral strategies in a manner that offers broad-spectrum efficacy, including against novel viruses, and a potentially higher barrier to viral escape. Despite their potential, HDAs are...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
635dc95f-53a2-5c35-85d1-e87b4a18f38e
DOI
10.1099/acmi.0.001167.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Meta-analysis of functional genomics studies reveals conserved cellular pathways required by viruses of pandemic concernDOI 10.1099/acmi.0.001167.v1
Meta-analysis of functional genomics studies reveals conserved cellular pathways required by viruses of pandemic concernSemantic proximity
Critical Nodes of Virus–Host Interaction Revealed Through an Integrated Network AnalysisSemantic proximity
The current landscape of coronavirus-host protein–protein interactionsSemantic proximity
High content screening and computational prediction reveal viral genes that suppress innate immune responseSemantic proximity
Network Medicine Approach to Viral Infections: Unraveling Universal and Virus-Specific Immune PathwaysSemantic proximity
High-Content Screening and Computational Prediction Reveal Viral Genes That Suppress the Innate Immune ResponseSemantic proximity
Virus-host interactomics: new insights and opportunities for antiviral drug discoverySemantic proximity
Genetic screens for the control of influenza virus replication: from meta-analysis to drug discoverySemantic proximity
Structural similarity-based prediction of host factors associated with SARS-CoV-2 infection and pathogenesisSemantic proximity
A Review of Omics Studies on Arboviruses: Alphavirus, Orthobunyavirus and PhlebovirusSemantic proximity
Comparison of viral RNA–host protein interactomes across pathogenic RNA viruses informs rapid antiviral drug discovery for SARS-CoV-2Semantic proximity
Conserved Filovirus Proteins as Targets of Broad-Spectrum AntiviralsSemantic proximity
Select a neighboring publication to make it the new centre.