Article

Looking for biomarkers in interferon response pathway to predict response to oncolytic HSV-1 in breast cancer: An ex vivo study

2022-12-14

Abstract excerpt

Breast cancer is the most common malignancy in women worldwide. Administration of oncolytic viruses is one of the novel promising cancer therapy approaches. Replication of these viruses is usually limited to cancer cells that have interferon (IFN) signaling defects. However, Interferon signaling is not completely impaired in all cancer cells which may limit the benefits of virotherapy. Identification of realistic...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6313f0d2-7792-56f8-84f8-c6026f77fa21
DOI: 10.21203/rs.3.rs-2350191/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Click a neighbor to travelStep 1 · 8 closest

Looking for biomarkers in interferon response pathway to predict response to oncolytic HSV-1 in breast cancer: An ex vivo studyDOI 10.21203/rs.3.rs-2350191/v1Read

Mutations in Human Interferon α2b Gene and Potential as Risk Factor Associated with Female Breast Cancer.Semantic proximity Read

PUMA and NF-kB Are Cell Signaling Predictors of Reovirus Oncolysis of Breast CancerSemantic proximity Read

An in silico approach uncovering the competency of oncolytic human adenovirus 52 for targeted breast cancer virotherapySemantic proximity Read

A novel immune checkpoint-related signature for prognosis and immune analysis in breast cancer.Semantic proximity Read

A comprehensive analysis based on classification of immunogenic cell death reveals immunologic and prognostic characteristics of breast cancerSemantic proximity Read

Exploiting gene expression profiles of circulating extracellular vesicles for breast cancer detectionSemantic proximity Read