Article

Functional Network Community Detection Can Disaggregate and Filter Multiple Underlying Pathways in Enrichment Analyses

2017-07-20

Abstract excerpt

Differential expression experiments or other analyses often end in a list of genes. Pathway enrichment analysis is one method to discern important biological signals and patterns from noisy expression data. However, pathway enrichment analysis may perform suboptimally in situations where there are multiple implicated pathways – such as in the case of genes that define subtypes of complex diseases. Our simulation s...

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Literature Corpus work: 62872006-0626-5f5b-aabe-55945190b26c
DOI: 10.1101/166207

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