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Article

Comprehensive molecular biomarker identification in breast cancer brain metastases.

Journal of translational medicine - 29 Dec 2017

Schulten Hans-Juergen, Bangash Mohammed, Karim Sajjad, Dallol Ashraf, Hussein Deema, Merdad Adnan, Al-Thoubaity Fatma K, Al-Maghrabi Jaudah, Jamal Awatif, Al-Ghamdi Fahad, Choudhry Hani, Baeesa Saleh S, Chaudhary Adeel G, Al-Qahtani Mohammed H

Abstract excerpt

BACKGROUND: Breast cancer brain metastases (BCBM) develop in about 20-30% of breast cancer (BC) patients. BCBM are associated with dismal prognosis not at least due to lack of valuable molecular therapeutic targets. The aim of the study was to identify new molecular biomarkers and targets in BCBM by using complementary state-of-the-art techniques. METHODS: We compared array expression profiles of three BCBM with...

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Source

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Identifiers

PMID: 29287594
DOI: 10.1186/s12967-017-1370-x
PMCID: PMC5747948

Genes

BRCA1
IDH2
BCL3
BNIP3
BRCA2
BRIP1
CASP14
CDH1
DMBT1
ERBB2
HAS2
HEPACAM
IDH1
JUN
LOXHD1
MMP3
MYCN
RAD51
TFF1
VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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