Article

Mutant Fam20c knock-in mice recapitulate both lethal and non-lethal human Raine Syndrome

2024-10-03

Abstract excerpt

<title>Abstract</title> <p>Inactivation or mutations of <italic>FAM20C</italic> causes human Raine Syndrome, which manifests as lethal osteosclerosis bone dysplasia or non-lethal hypophosphatemia rickets. However, it is only hypophosphatemia rickets that was reported in the mice with <italic>Fam20c</italic> deletion or mutations. To further investigate the local and global impacts of <italic>Fam20c</italic> mutat...

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Literature Corpus work: 61e4f5f5-7a4a-5f24-b159-79dc708733d5
DOI: 10.21203/rs.3.rs-5012153/v1

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