Article

Characterization of regulatory transcriptional mechanisms in hepatocyte lipotoxicity

2021-03-24

Abstract excerpt

Non-alcoholic fatty liver disease is a continuum of disorders among which non-alcoholic steatohepatitis (NASH) is particularly associated with a negative prognosis. Hepatocyte lipotoxicity is one of the main pathogenic factors of liver fibrosis and NASH. However, the molecular mechanisms regulating this process are poorly understood. The main aim of this study was to dissect transcriptional mechanisms regulated by...

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Literature Corpus work: 61e21f5c-dc6d-561e-87ff-4b7f0bb83779
DOI: 10.1101/2021.03.24.436772

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