Article

Parasitoid wasp venom elevates sorbitol and alters expression of metabolic genes in human kidney cells

2018-06-20

Abstract excerpt

Venom from the parasitoid wasp Nasonia vitripennis dramatically elevates sorbitol levels in its natural fly hosts. In humans, sorbitol elevation is associated with complications of diabetes. Here we demonstrate that venom also induces this disease-relevant phenotype in human cells, and investigate possible pathways involved. Key findings are that (a) low doses of Nasonia venom elevate sorbitol levels in human re...

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Identifiers and source

Literature Corpus work: 6178a873-60e4-5af6-bf9f-2d47a551e98c
DOI: 10.1101/351031

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