Article

<i>Aedes aegypti</i> Malpighian tubules are immunologically activated following systemic Toll activation

2022-08-22

Abstract excerpt

<h4>Background</h4> Canine heartworm is a widespread and potentially fatal mosquito-borne disease caused by infections with the parasitic nematode, Dirofilaria immitis . We have previously shown that systemic activation of the Toll immune pathway via silencing of the negative regulator Cactus in Aedes aegypti blocks parasite development in the Malpighian tubules, the mosquito renal organ. However, it was not e...

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Literature Corpus work: 61082256-181a-52e7-ab50-09a62b8eef30
DOI: 10.1101/2022.08.21.504691

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