Article

Human promoter analysis of the Programmed Axon Death genes <i>NMNAT2</i> and <i>SARM1</i>

2026-03-25

Abstract excerpt

SARM1 and NMNAT2 are two well described players in the Programmed Axon Death (PAxD) pathway. However, less is known about their transcriptional regulation, especially in humans, despite evidence that their expression levels influence axon vulnerability and thus modulation of expression presents a potential therapeutic target. Here, we used in-cell luciferase assays to functionally study the promoter regions of the...

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Identifiers and source

Literature Corpus work: 60ec784c-dda3-5f17-975f-f612a8e632d8
DOI: 10.64898/2026.03.23.712947

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