Article

Control of cytokinesis by β-adrenergic receptors indicates an approach for regulating cardiomyocyte endowment

2019-10-04

Abstract excerpt

<h4>ABSTRACT/SUMMARY</h4> One million patients with congenital heart disease (CHD) live in the US. They have a lifelong risk of developing heart failure. Current concepts do not sufficiently address mechanisms of heart failure development specifically for these patients. We show that cardiomyocyte cytokinesis failure is increased in tetralogy of Fallot with pulmonary stenosis (ToF/PS), a common form of CHD. Label...

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Literature Corpus work: 607ee432-3756-5ded-9276-fffc75ec8105
DOI: 10.1101/782920

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